MCM3抗体MCM3兔多抗抗体RLFB antibody抗体

保存缓冲液

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

功能

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \'once per cell cycle\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.