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LRP4抗体LRP4兔多抗抗体Multiple epider

mal growth factor-like domains 7 antibody抗体LRP4 Antibody抗体
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  • ¥440 - 1320
  • CUSABIO已认证
  • CN
  • CSB-PA013099ESR1HU
  • 2025年07月11日
  • ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant Human Low-density lipoprotein receptor-related protein 4 protein (1500-1725AA)

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.

    • 克隆性

      Polyclonal

    • 标记物

      Non-conjugated

    • 适应物种

      Human

    • 保质期

      6个月

    • 抗原来源

      Homo sapiens (Human)

    • 目录编号

      O75096

    • 级别

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 宿主

      Rabbit

    • 应用范围

      ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

    • 浓度

      >95%,Antigen Affinity Purified

    • 靶点

      LRP4

    • 抗体英文名

      LRP4 Antibody

    • 抗体名

      Multiple epidermal growth factor-like domains 7 antibody

    • 规格

      100μl/50μl/20μl

    规格:100μl产品价格:¥1320.0
    规格:50μl产品价格:¥880.0
    规格:20μl产品价格:¥440.0

    保存缓冲液

    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

    功能

    Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes.

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    文献支持
    LRP4抗体LRP4兔多抗抗体Multiple epidermal growth factor-like domains 7 antibody抗体LRP4 Antibody抗体
    ¥440 - 1320