RNF128抗体RNF128兔多抗抗体RING-type E
3 ubiquitin transferase RNF128抗体RNF128 Antibody, HRP conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA837448LB01HU
- 2025年07月10日
- ELISA
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
HRP
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q8TEB7
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
RNF128
- 抗体英文名：
RNF128 Antibody, HRP conjugated
- 抗体名：
RNF128;E3 ubiquitin-protein ligase RNF128;Gene related to anergy in lymphocytes protein;GRAIL;RING finger protein 128;RING-type E3 ubiquitin transferase RNF128
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural-inducing signals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Studies of the Ubiquitin Proteasome System
of E3 Enzymes Expressed in In Vitro Translation Systems Alternate Protocol 2: Determination of Ubiquitin Chain Variant Phenotype Basic Protocol 7: Chelation of Zinc from RING‐ and PHD‐Finger E3s Alternate Protocol 3: Inhibition of HECT Domain E3
Functional Assays on High‐Content Protein Microarrays
?protein interactions, protein?DNA interactions, protein?phospholipid interactions, small?molecule targets, substrates of protein kinases, substrates of ubiquitin E3 ligases, and substrates of methyltransferase. This article provides a detailed illustration
Overview of Protein Microarrays
gluconeogenesis. Cell 136:1073‐1084. Lu, J.‐Y., Lin, Y.‐Y., Qian, J., Tao, S.‐C., Zhu, J., Pickart, C., and Zhu, H. 2008. Functional dissection of a HECT ubiquitin E3 Ligase. Mol. Cell
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