Trim21抗体Trim21兔多抗抗体Tripartite
motif-containing protein 21 antibody抗体Trim21 Antibody, Biotin conjugated抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA733816LD01MO
- 2025年07月16日
- ELISA
- Rabbit
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Mouse E3 ubiquitin-protein ligase TRIM21 protein (1-470AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Biotin
- 适应物种：
Mouse
- 保质期：
6个月
- 抗原来源：
Mus musculus (Mouse)
- 目录编号：
Q62191
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA
- 浓度：
>95%,Protein G purified
- 靶点：
Trim21
- 抗体英文名：
Trim21 Antibody, Biotin conjugated
- 抗体名：
Tripartite motif-containing protein 21 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr-187' phosphorylated-form), thereby promoting its degradation by the proteasome. Monoubiquitinates IKBKB that will negatively regulates Tax-induced NF-kappa-B signaling. Negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. Mediates the ubiquitin-mediated proteasomal degradation of IgG1 heavy chain, which is linked to the VCP-mediated ER-associated degradation (ERAD) pathway. Promotes IRF8 ubiquitination, which enhanced the ability of IRF8 to stimulate cytokine genes transcription in macrophages. Plays a role in the regulation of the cell cycle progression. Enhances the decapping activity of DCP2. Exists as a ribonucleoprotein particle present in all mammalian cells studied and composed of a single polypeptide and one of four small RNA molecules. At least two isoforms are present in nucleated and red blood cells, and tissue specific differences in RO/SSA proteins have been identified. The common feature of these proteins is their ability to bind HY RNAs.2.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验长期以来医学界认为，人体免疫系统对已进入细胞内部的病毒束手无策。但英国一项最新研究发现，一些抗体能够随病毒进入人体细胞内部，并在细胞内一种蛋白质的作用下引发摧毁病毒的连锁反应，这一发现将有助于研发新的抗病毒药物。 位于英国剑桥的分子生物学实验室等机构研究人员在新一期美国《国家科学院学报》上报告说，他们发现人体免疫系统生成的抗体在血液中遇到病毒后，会一直附着其上，即使一些病毒穿过细胞膜进入了人体细胞，抗体也仍然附着于这些病毒表面。而人体细胞内部一种名为ＴＲＩＭ２１
Using the Gibbs Motif Sampler to Find Conserved Domains in DNA and Protein Sequences
program. Keywords: Gibbs sampling; Transcription factor binding site; Sequence Alignment; Motif; DNA; Protein; Phylogentic Footprinting; Stochastic Algorithm; Markov Chain Monte?Carlo; Bayesian statistics
Mapping Protein Distributions on Polytene Chromosomes by Immunostaining
Reagents Ammonium sulfate (50% [w/v]) (optional, see Step 23) Antibodies, primary Affinity-purified primary antibodies are diluted in PBS containing 1% BSA. The dilutions must be adjusted for each individual primary antibody. Typical
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