- ￥2024
- CUSABIO
- CN
- CSB-PA228665
- 2025年07月13日
- ELISA,WB,IHC,IF;WB:1:500-1:1000,IHC:1:50-1:200,IF:1:100-1:200
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around aa.254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A.
- 亚型：
/
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
/
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q12778
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB,IHC,IF;WB:1:500-1:1000,IHC:1:50-1:200,IF:1:100-1:200
- 浓度：
>95%,Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 靶点：
FOXO1
- 抗体英文名：
FOXO1 (Ab-256) Antibody
- 抗体名：
/
- 规格：
100μl
保存缓冲液
/功能
FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14
Gan L, et al. (2005) J Neurochem; 93(5): 1209-19.
Smith WW, et al. (2005) J Cell Biol; 169(2): 331-9.
Di Maira G, et al. (2005) Cell Death Differ; 12(6): 668-77.
Horn S, et al. (2004) Leukemia; 18(11): 1839-49.
Zhao X, et al. (2004) Biochem J 4; 378(Pt 3): 839-49.
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文献和实验
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