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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Potassium voltage-gated channel subfamily A member 6 protein (1-171AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P17658
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度:
>95%,Protein G purified
- 靶点:
KCNA6
- 抗体英文名:
KCNA6 Antibody
- 抗体名:
KCNA6;Potassium voltage-gated channel subfamily A member 6;Voltage-gated potassium channel HBK2;Voltage-gated potassium channel subunit Kv1.6
- 规格:
100μg/50μg/20μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
| 规格: | 20μg | 产品价格: | ¥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
功能
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (PubMed:2347305, PubMed:14575698). The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:2347305, PubMed:14575698). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA6, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation. Homotetrameric channels display rapid activation and slow inactivation (PubMed:2347305).风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Modulation of Potassium Ion Channel Proteins Utilising Antibodies
roles within native neurones. Utilising this approach, we have investigated the role of the voltage-gated potassium channel Kv3.1b subunit within a region of the brainstem important in the regulation of autonomic function. We provide some useful control
Identification of Mutations in the Kir6.2 Subunit of the KATP Channel
The beta-cell ATP-sensitive potassium channel is a key component of stimulus —secretion coupling in the pancreatic beta-cell. The channel consists of four subunits of the inwardly rectifying potassium channel Kir6.2 and four subunits
subunit of the human brain large-conductance, voltage-activated, calcium-sensitive potassium channel (BK channel) are loaded with Rb+ , washed, and then incubated under experimental conditions. The cell supernatant is removed, and the remaining cell
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