相关产品推荐更多 >

UBA1抗体UBA1兔多抗抗体Ubiquitin-like modifier-activating enzyme 1 antibody抗体UBA1 Antibody, Biotin conjugated抗体
¥880
MYH4抗体MYH4兔多抗抗体/抗体MYH4 Antibody抗体
¥2024
KRT6A抗体KRT6A兔多抗抗体Type-II keratin Kb6 antibody抗体KRT6A Antibody, Biotin conjugated抗体
¥880
MYH7B抗体MYH7B兔多抗抗体Slow A MYH14 antibody抗体MYH7B Antibody, Biotin conjugated抗体
¥880
EFCAB1抗体EFCAB1兔多抗抗体EFCB1_HUMAN antibody抗体EFCAB1 Antibody, FITC conjugated抗体
¥880
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized non-phosphopeptide derived from Human SNAI1 around the phosphorylation site of serine 246 (T-F-S(p)-R-M).
- 亚型:
/
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
/
- 适应物种:
Human,Mouse
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
O95863
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB;WB:1:500-1:3000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
SNAI1
- 抗体英文名:
SNAI1 (Ab-246) Antibody
- 抗体名:
/
- 规格:
100μl
保存缓冲液
/功能
Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.Okubo T., Cancer Res. 61:1338-1346(2001).
Twigg S.R., Hum. Genet. 105:320-326(1999).
Paznekas W.A., Genomics 62:42-49(1999)
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
更多文献信息可以查看cusabio官网
技术资料暂无技术资料 索取技术资料
文献支持
SNAI1抗体SNAI1兔多抗抗体/抗体SNAI1 (Ab-246) Antibody抗体
¥2024





