- ￥1100 - 1980
- CUSABIO
- CN
- CSB-PA984353
- 2025年07月12日
- ELISA,IHC;ELISA:1:1000-1:2000,IHC:1:10-1:50
- Rabbit
- Human
企业认证
相关产品推荐更多 >
MYOF抗体MYOF一抗抗体Myoferlin antibody抗体MYOF Antibody抗体
￥3900
RND2抗体RND2一抗抗体RND2_HUMAN antibody抗体RND2 Antibody抗体
￥3900
FMOD抗体FMOD兔多抗抗体SLRR2E antibody抗体FMOD Antibody, Biotin conjugated抗体
￥880
MRE11抗体MRE11一抗抗体OTTHUMP00000236833 antibody抗体MRE11A Antibody抗体
￥880
DRD1抗体DRD1兔多抗抗体Dopamine D1 receptor抗体DRD1 Antibody抗体
￥440
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthetic peptide of Human ABCC1
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
/
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P33527
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,IHC;ELISA:1:1000-1:2000,IHC:1:10-1:50
- 浓度：
>95%,Antigen affinity purification
- 靶点：
ABCC1
- 抗体英文名：
ABCC1 Antibody
- 抗体名：
Multiple drug resistance protein 1 antibody
- 规格：
100μl/50μl
| 规格： | 100μl | 产品价格： | ￥1980.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Fluorescence Studies of Drug Binding and Translocation by Membrane Transporters
Resistance to multiple drugs is a serious limitation to chemotherapy treatment of human cancers. In addition, many clinically useful drugs show limited uptake in the intestine and cannot gain access to the brain. Three multidrug efflux pumps
STM：广州医科大学刘铭/谢茂彬合作发现肝细胞癌的新潜在治疗靶点 Claudin 6
显示，CLDN6 可以稳定 YAP1，促进其核转位，从而活化 Hippo 通路。 IP 结果显示 CLDN6 与 YAP1 竞争性结合 TJP2 鉴于 CLDN6 是多次跨膜蛋白，但其不具有（或尚未发现？）配体结合结构域，难以设计小分子药物；而如果使用单抗的话，由于肝细胞癌具有复杂的微环境， T 细胞难以发挥足够的抗体依赖细胞毒性（ADCC）效应杀伤癌细胞。因此，作者设计了靶向 CLDN6 的抗体偶联药物（Antibody-Drug Conjugate, ADC），将细胞毒性药物 DM1 和 CLDN6 抗体
, which results in the display of a target-specificity-conferring peptide or protein on the phage coat, can be used to design the drug-release mechanism and is not described herein. However, the methods used to chemically conjugate cytotoxic drugs at high density
技术资料暂无技术资料 索取技术资料
