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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Fusion protein of Human GPA33
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q99795
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,IHC;ELISA:1:2000-1:5000,IHC:1:50-1:200
- 浓度:
>95%,Antigen affinity purification
- 靶点:
GPA33
- 抗体英文名:
GPA33 Antibody
- 抗体名:
Transmembrane glycoprotein A33 antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥1100.0 |
保存缓冲液
-20℃, pH7.4 PBS, 0.05% NaN3, 40% Glycerol功能
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验- Monoclonal antibody- Source: Dakopatts- Dilution 1:20- Antigen retrieval method: Protease I treatment for 12 minutes- Staining pattern: Cell membrane- MOC-31 reacts with a transmembrane glycoprotein present on most normal and malignant epithelia
High-Level Expression of a Phage Display-Derived scFv in Pichia pastoris
of a phage display-derived scFv in Pichia pastoris . The phage display-derived antibody A33scFv recognizes a cell surface glycoprotein (designated A33) expressed in colon cancer that serves as a target antigen for radioimmunoimaging and/or immunotherapy
类细胞为效应细胞来构建双特异抗体更为常见:第一.T细胞群中存在着免疫记忆细胞;第二.有证据表明在恶性肿瘤患者体内存在着肿瘤特异性的T细胞;第三.体内外实验表明抗CD3抗体激活的杀伤细胞(CD3AK)比IL-2激活的杀伤细胞(LAK)具有更强大的细胞毒效应[2]。体内外生物学实验结果表明:Diabody能同时与T细胞和癌细胞结合,并通过激活T细胞,来靶向杀灭癌细胞[3,4]。HIT3a[5]和PHMA02[6]是我所研制的鼠源性抗CD3和抗Pgp(P-glycoprotein)单克隆抗体,我们在克隆单克隆抗体
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