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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from Human PKR around the phosphorylation site of T446.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P19525
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
WB, ELISA; WB:1:500-1:2000, ELISA:1:10000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
EIF2AK2
- 抗体英文名:
Phospho-EIF2AK2 (T446) Antibody
- 抗体名:
Tyrosine protein kinase EIF2AK2 antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验在肿瘤生长中的作用。研究发现,抑制垂体中 POMC 的表达对荷瘤小鼠没有明显的毒性,并且抑制了 LLC 肿瘤的生长,同时增强了肿瘤中 CD8+T、CD4+T、NK 和 NKT 细胞的浸润,IFN-γ 也在这些免疫细胞中表达上调(图 2 A-D)。然而,补充 α-MSH 逆转了 POMC 的表达抑制对肿瘤生长和抗肿瘤免疫的影响。采用抗 CD4 和抗 CD8 抗体处理小鼠,耗尽肿瘤中 CD4+ 和 CD8+T 细胞,结果发现也消除了敲低 POMC 对肿瘤生长抑制的作用(图 2 E)。结果说明,抑制垂体中
Raf-1 Protein Kinase Activity in T Cells from Aged Mice
Most of our models of signal transduction through the T-cell receptor (TCR) involve components and pathways first described in T-cell clones and T-cell lymphomas such as the Jurkat cell line (1 ). These studies, while providing valuable
Protein Kinase A and Signal Transduction in T Lymphocytes: Biochemical and Molecular Methods
Abnormal T-cell effector functions in systemic lupus erythematosus (SLE) are present and may be associated with disease immunopathogenesis. Our work has led to the characterization of a signaling defect, involving protein kinase A (PKA), leading
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