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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from Human FAS around the phosphorylation site of Y291.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P25445
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
IF, ELISA; IF:1:200-1:1000, ELISA:1:5000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
FAS
- 抗体英文名:
Phospho-FAS (Y291) Antibody
- 抗体名:
FAS;APT1;FAS1;TNFRSF6;Tumor necrosis factor receptor superfamily member 6;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;FASLG receptor;CD antigen CD95
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验Electroporation is a method for introducing DNA into cells by using a high-voltage electric field. This method is very simple and easily manipulated. We describe here a method for the modification of tumor cells with the Fas/Apo-1 (CD95) antigen
细胞凋亡的启动。与此相反, ced-9基因产物可以保护细胞不至发生凋亡。换言之,当ced-3和ced-4蛋白水平较高, 而ced-9蛋白表达量较低时,细胞凋亡易于发生。在哺乳动物系统中,bcl-2原癌基因与ced-9具有类似的功能,可通过阻止凋亡的发生而延长细胞存活时间。另一种哺乳动物基因产物p53则被认为是一种肿瘤抑制基因, 因其可诱导肿瘤细胞凋亡的发生。p53缺失或突变均可导致细胞的恶性转化或永生化。Fas(CD95/Apo-1)为一种细胞表面受体基因,广泛表达于机体多种组织细胞(尤其是免疫细胞)表面
/Western blotting assays. Another factor important in achieving optimal results is the degree of sensitivity of cells to the antibody-induced apoptosis. As an example, CD95 (Fas)-induced apoptosis of human Jurkat cell line by monoclonal antibody EOS
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