Recombinant proteins of human IDH1 (amino acids 1-240).
规格:
100μl
IDH1 [26136] [100 µL]
Catalog Number: 26136
Gene Symbol: IDH1
Description: Anti-IDH1 Mouse Monoclonal Antibody
Background: Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors.
Immunogen: Recombinant proteins of human IDH1 (amino acids 1-240).
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti-IDH1 antibody recognizes IDH1 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
Download Datasheet:
Western blot:
Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat.#10198) was blotted with anti-IDH1 mouse antibody (Cat.# 26136).