Amygdalin苦杏仁苷,29883-15-6

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Amygdalin

CAS No. : 29883-15-6

MCE 国际站：Amygdalin

产品活性：扁桃素是从蔷薇果实的果核中分离的植物葡萄糖苷，例如杏，桃，杏仁，樱桃和李子。

研究领域：Others

作用靶点：Others

In Vitro: Amygdalin has antitumor activity. Some advances had been made on the antitumor mechanism of amygdalin. Amygdalin downregulates especially genes belonging to cell cycle category: exonuclease 1, ATP-binding cassette, sub-family F, member 2, MRE11 meiotic recombination 11 homolog A, topoisomerase (DNA) I, and FK506 binding protein 12-rapamycin-associated protein 1. RT-PCR analysis reveals that mRNA levels of these genes are also decreased by amygdalin treatment in SNU-C4 human colon cancer cells.

In Vivo: Amygdalin is effective at alleviating inflammatory pain and that it can be used as an analgesic with anti-nociceptive and anti-inflammatory activities. The intramuscular injection of amygdalin significantly reduced the formalin-induced tonic pain in both early (the initial 10 min after formalin injection) and late phases (10-30 min following the initial formalin injection). During the late phase, amygdalin reduces the formalin-induced pain in a dose-dependentmanner in a dose range less than 1 mg/kg.

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