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500ug
| 产品编号 | bs-1235P |
| 英文名称 | HYAL1 Antibody Blocking Peptide |
| 中文名称 | 透明质酸酶/玻璃酸酶封闭多肽 |
| 英文别名 | HYA1; HYAL PH-20; HYAL PH20; HYAL1; HYAL3; HYAL5; Haase; Hyaluronidase PH-20; MGC26532; PH-20 Hyaluronidase; PH20; Hyaluronidase PH20; PH20 Hyaluronidase; SPAG15; SPAM-1; SPAM1;Sperm adhesion molecule 1; Sperm surface protein PH-20; Sperm surface protein PH20; zona pellucida binding. LUCA-3; HYAL1_HUMAN; HYAL 1; Hyal-1; HYAL1; HYAL1_HUMAN; Hyaluronidase 1; Hyaluronidase-1; Hyaluronoglucosaminidase 1; Hyaluronoglucosaminidase-1; Hyaluronoglucosaminidase1; LUCA 1; LUCA-1; LUCA1; Lung carcinoma protein 1; MGC45987; NAT6; Plasma hyaluronidase; Tumor suppressor LUCA 1. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Invasion/microenvironment > ECM > Extracellular matrix Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > Other Enzymes Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Glucosaminoglycans |
| 亚细胞定位 | Secreted. Lysosome. |
| 组织特异性 | Highly expressed in liver, kidney, lung and skin. |
| 相似性 | Belongs to the glycosyl hydrolase 56 family.
Contains 1 EGF-like domain. |
| 功能 | May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Hyaluronidase degrades hyaluronic acid, which is an important structural proteoglycan found in basement membranes and also extracellular matrices. There are six members of the hyaluronidase family. Hyaluronidase PH20 is a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane and plays a role in sperm penetration through the the hyaluronic acid-rich cumulus cell layer surrounding the oocyte. Abnormal expression of this gene has been implicated in degradation of basement membranes leading to tumor invasion and metastasis. |
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HYAL1 Antibody Blocking Peptide(bs-1235P)-500ug
¥880







