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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-17320R |
| 英文名称 | TMEFF1 Rabbit pAb |
| 中文名称 | TMEFF1蛋白抗体 |
| 英文别名 | Tomoregulin-1 precursor; C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; Tomoregulin-1; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain. |
| 中文别名 | |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TEFF1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 37 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | May interact with ST14. |
| 亚细胞定位 | Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted. |
| 组织特异性 | Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. |
| 相似性 | Belongs to the tomoregulin family. Contains 1 EGF-like domain. Contains 2 Kazal-like domains. |
| 功能 | May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Tomoregulin-1 precursor is a single-pass type I membrane protein thought to be a tumor suppressor in brain cancers. Its expression is down-regulated in these tumors as compared to control brain tissues. In addition, it might also inhibit NODAL and BMP signaling during neural patterning. There are 2 isoforms produced by alternative splicing. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Testis (Mouse) Lysate at 40 ug
Primary: Anti-TEFF1 (bs-17320R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
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