GPR172A Rabbit pAb(bs-16293R)-50ul/100ul/200ul

GPR172A Rabbit pAb(bs-16293R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-16293R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-16293R
    英文名称GPR172A Rabbit pAb
    中文名称GPR172A蛋白抗体
    英文别名GPR172A; hRFT3; PAR1; PERV-A receptor 1; Porcine endogenous retrovirus A receptor 1; Protein GPR172A; RFT3; RFT3_HUMAN; Riboflavin transporter 3.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Dog, Pig, Cow, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GPR172A
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量46 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cell membrane.
    组织特异性Highly expressed in brain, fetal brain and salivary gland. Weakly expressed in other tissues.
    相似性Belongs to the riboflavin transporter family.
    功能Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    GPR172A Rabbit pAb(bs-16293R)-
    Sample:
    Cerebrum (Mouse) Lysate at 40 ug
    Cerebrum (Rat) Lysate at 40 ug
    Primary: Anti- GPR172A (bs-16293R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 46 kD
    Observed band size: 48 kD

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