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产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-16229R |
| 英文名称 | GALNTL6 Rabbit pAb |
| 中文名称 | GALNTL6蛋白抗体 |
| 英文别名 | EC 2.4.1.41; GalNAc transferase 17; GalNAc-T17; GALNACT20; GALNTL6; GaNTase 17; GLTL6_HUMAN; MGC44629; OTTHUMP00000219021; OTTHUMP00000219023; Polypeptide GalNAc transferase 17; Polypeptide N-acetylgalactosaminyltransferase-like 6; polypeptide N-acetylgalactosaminyltransferase-like 6 UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 20; pp-GaNTase 17; Protein-UDP acetylgalactosaminyltransferase 17; Putative polypeptide N-acetylgalactosaminyltransferase 17; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Rat (Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GALNTL6 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 70 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Metabolism > Amino Acids Signal Transduction > Protein Trafficking > Golgi Proteins |
| 亚细胞定位 | Golgi apparatus membrane. |
| 相似性 | Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. |
| 功能 | GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Testis(Rat) Lysate at 40 ug
Primary: Anti-GALNTL6 (bs-16229R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kD
Observed band size: 70 kD
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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