ADGRE2 | EMR2 Rabbit pAb(bs-13634R)-50ul/100ul/200ul产品图

ADGRE2 | EMR2 Rabbit pAb(bs-13

634R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-13634R
  • 2026年10月14日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-13634R
    英文名称EMR2 Rabbit pAb
    中文名称CD312抗体
    英文别名CD 312; CD 312 antigen; CD312; CD312 antigen; Egf like module containing mucin like hormone receptor like 2; Egf like module containing mucin like hormone receptor like sequence 2; EGF like module EMR2; EGF-like module receptor 2; EGF-like module-containing mucin-like hormone receptor-like 2; EMR2; EMR2_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human EMR2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量88 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cell membrane.
    组织特异性Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested.
    翻译后修饰modificationsAutoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
    相似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    _x000D_ Contains 5 EGF-like domains.
    Contains 1 GPS domain.
    功能Receptor probably involved in cell attachment.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The epidermal growth factor (EGF) family constitutes a group of class B, G protein-coupled receptors, which includes CD97 and EMR2. EMR2 is a member of the EGF-TM7 receptor subfamily. EGF-TM7 receptors are a family of class B, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system. Within the TM7 superfamily, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique. Derived from the processing of a single polypeptide, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety. Through a variable number of N-terminal EGF-like domains, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate. EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes. EMR2 is proteo-lytically cleaved into two separate subunits: a seven-transmembrane subunit, and an extracellular Alpha subunit.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    _x000D_ Sample:
    _x000D_ TM4(Mouse) Cell Lysate at 30 ug
    _x000D_ MCF-7(Human) Cell Lysate at 30 ug
    _x000D_ Primary: Anti-EMR2 (bs-13634R) at 1/300 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 88 kD
    _x000D_ Observed band size: 128 kD

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    ADGRE2 | EMR2 Rabbit pAb(bs-13634R)-50ul/100ul/200ul
    ¥1180 - 2800