HCCS | CCHL Rabbit pAb(bs-15424R)-50ul/100ul/200ul产品图

HCCS | CCHL Rabbit pAb(bs-1542

4R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-15424R
  • 2026年10月14日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-15424R
    英文名称HCCS Rabbit pAb
    中文名称全细胞色素C合成酶抗体
    英文别名CCHL; DKFZp779I1858; EC 4.4.1.17; Holocytochrome c synthase(cytochrome c heme lyase); Holocytochrome c type synthase; MCOPS7; RGD1563855; RP23-37L2.1; CCHL_HUMAN.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Dog, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human HCCS
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量31 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cytochromes

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Cytochromes

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Signal Transduction > Metabolism > Mitochondrial

    亚细胞定位Mitochondrion inner membrane (Potential).
    相似性Belongs to the cytochrome c-type heme lyase family.
    Contains 2 HRM (heme regulatory motif) repeats.
    功能Links covalently the heme group to the apoprotein of cytochrome c (By similarity).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HCCS) Polyclonal Antibody, Unconjugated (bs-15424R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Holocytochrome c type synthase; HCCS) Polyclonal Antibody, Unconjugated (bs-15424R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining._x000D_ _x000D_

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    HCCS | CCHL Rabbit pAb(bs-15424R)-50ul/100ul/200ul
    ¥1180 - 2800