ANKRD13B Rabbit pAb(bs-9745R)-50ul/100ul/200ul产品图

ANKRD13B Rabbit pAb(bs-9745R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-9745R
  • 2026年10月14日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-9745R
    英文名称ANKRD13B Rabbit pAb
    中文名称锚蛋白重复结构域蛋白13B抗体
    英文别名Ankrd13b; ANKRD13B(ankyrin repeat domain 13B); ankyrin repeat domain 13B; AN13B_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Chicken, Pig, Cow, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ANKRD13B
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量70 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    相似性Contains 2 ANK repeats.
    Contains 3 UIM (ubiquitin-interacting motif) repeats. _x000D_
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes can lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD13B (ankyrin repeat domain 13B) is a 626 amino acid protein that contains two ANK repeats and three ubiquitin-interacting motif (UIM) repeats. Conserved in dog, cow, mouse and rat, ANKRD13B exists as two alternatively spliced isoforms. The gene that encodes ANKRD13B maps to human chromosome 17, which makes up over 2.5% of the human genome, with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is recognized as a genetic determinant of early onset breast cancer. Chromosome 17 is also linked to neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    _x000D_ SY5Y(Human) Cell Lysate at 30 ug
    _x000D_ Primary: Anti- ANKRD13B (bs-9745R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 70kD
    _x000D_ Observed band size: 70 kD
    _x000D_
    产品细节图片2
    Sample:
    _x000D_ Hippocampus (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti-ANKRD13B (bs-9745R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 70 kD
    _x000D_ Observed band size: 72 kD
    _x000D_
    产品细节图片3
    Sample:
    _x000D_ Cerebrum (Mouse) Lysate at 40 ug
    _x000D_ Cerebellum (Mouse) Lysate at 40 ug
    _x000D_ SH-SY5Y(Human) Cell Lysate at 30 ug
    _x000D_ Primary: Anti- ANKRD13B (bs-9745R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 70 kD
    _x000D_ Observed band size: 70 kD

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