Sample: A549 (human)Cell Lysate at 40 ug
Primary: Anti- HEXDC(bs-8418R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54kD
Observed band size: 48kD
- ￥1180 - 2800
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- bs-8418R
- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-8418R |
| 英文名称 | HEXDC Rabbit pAb |
| 中文名称 | 氨基己糖苷酶D抗体 |
| 英文别名 | beta hexosaminidase D; beta N acetylhexosaminidase; FLJ23825; Hexosaminidase(glycosyl hydrolase family 20 catalytic domain) containing; hexosaminidase(glycosyl hydrolase family 20, catalytic domain; Hexosaminidase D; Hexosaminidase domain containing protein; N acetyl beta galactosaminidase; HEXDC_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human HEXDC |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 54 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Homodimer; disulfide-linked (By similarity). |
| 亚细胞定位 | Cytoplasmic and Nuclear |
| 相似性 | Belongs to the glycosyl hydrolase 20 family. |
| 功能 | Has hexosaminidase activity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample: HepG2 (human)Cell Lysate at 40 ug
Primary: Anti- HEXDC(bs-8418R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54kD
Observed band size: 48kD
Primary: Anti- HEXDC(bs-8418R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54kD
Observed band size: 48kD
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HEXDC Rabbit pAb(bs-8418R)-50ul/100ul/200ul
￥1180 - 2800
