Sample:HepG2 (Human)Cell Lysate at 40 ug
Primary: Anti-DIRC2(bs-8278R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 52kD
Observed band size: 52kD
- ￥1180 - 2800
- Bioss
- bs-8278R
- 2025年10月16日
- 产品信息以Bioss网站为准
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-8278R |
| 英文名称 | DIRC2 Rabbit pAb |
| 中文名称 | 干扰肾细胞癌蛋白2抗体 |
| 英文别名 | Disrupted in renal carcinoma protein 2; DIRC 2; Disrupted in renal cancer protein 2; Disrupted in renal carcinoma 2; FLJ14784; NP_116228; RCC 4; RCC4; Renal cell carcinoma 4; DIRC2_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Pig, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DIRC2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 52 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Lysosome membrane; Multi-pass membrane protein. |
| 组织特异性 | Ubiquitous. Expressed in proximal tubular cells of the kidney. |
| 翻译后修饰 | Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment. |
| 相似性 | Belongs to the major facilitator superfamily. |
| 功能 | Electrogenic metabolite transporter. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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DIRC2 Rabbit pAb(bs-8278R)-50ul/100ul/200ul
￥1180 - 2800
