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- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11994R |
| 英文名称 | phospho-Serine/Threonine Rabbit pAb |
| 中文名称 | 磷酸化丝氨酸/苏氨酸抗体 |
| 英文别名 | phosphoserine/threonine; phospho-Ser/phospho-Thr; pan phospho-Ser/phospho-Thr; pan-phospho-Ser/phospho-Thr; pS/pT; p-S/p-T; pSER/pThr; p-SER/p-Thr; p-Sp-T; pan pS/pT; pan p-S/p-T; pan pSER/pThr; pan p-SER/p-Thr; pan p-Sp-T.. |
| 中文别名 | 泛磷酸化丝氨酸/苏氨酸抗体; 丝氨酸/苏氨酸泛磷酸化; pan 磷酸化丝氨酸/苏氨酸; pan-磷酸化丝氨酸/苏氨酸; 泛丝氨酸磷酸化; 泛苏氨酸磷酸化; 泛丝氨酸/苏氨酸磷酸化; |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Species independent |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthesised phosphopeptide contain Phosphoserine and Phosphothreonine |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism Neuroscience > Neurotransmission > Intracellular Signaling > Phosphatases Signal Transduction > Metabolism > Amino Acids Signal Transduction > Protein Phosphorylation > Tyrosine Phosphatases |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Protein phosphorylation provides a signalling system that can be thought of as a kind of protein on/off switch for many cellular signalling pathways. Phosphorylation is observed on serine, threonine, tyrosine and histidine residues. Cellular networks underlying phosphorylation can be very complex and often occurs on multiple distinct sites on a given protein. Phospho-specific antibodies are becoming critical reagents both for basic research and for clinical diagnosis. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 5.26 }}] {Li et al. MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation. (2018) Mol.Oncol. 12:391-405} {WB} {Human}
Technology (reference 9386). It recognizes phosphorylated threonine residues in a manner largely independent of the surrounding amino-acid sequence. The antibody is phospho-specific but does not cross-react with phospho-serine-containing sequences. The anti
. 1. Introduction Glycogen synthase kinase (GSK)-3 is a serine/threonine proteinkinase which was first described as a component of insulin-mediatedsignaling pathway (1) . There are two homologous mammalianisoforms, encoded by different genes, GSK-3a and GSK
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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