Sample:
Testis (Mouse) Lysate at 40 ug
Primary: Anti- DULLARD (bs-11828R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 28 kD
Observed band size: 25 kD
- ￥1180 - 2800
- Bioss
- bs-11828R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11828R |
| 英文名称 | DULLARD Rabbit pAb |
| 中文名称 | DULLARD蛋白抗体 |
| 英文别名 | Dullard homolog; HSA 011916; NET 56 antibodySerine threonine protein phosphatase dullard; CNEP1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Cow, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DULLARD |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 28 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with CNEP1R1; the complex dephosphorylates LPIN1 and LPIN2. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. Nuclear membrane; Single-pass membrane protein. |
| 组织特异性 | Muscle specific with lower expression in other metabolic tissues. |
| 相似性 | Belongs to the dullard family. Contains 1 FCP1 homology domain. |
| 功能 | DULLARD is a serine/threonine phosphatase which may be required for proper nuclear membrane morphology. It is involved in LPIN1 dephosphorylation and may antagonize BMP signaling. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92% sequence identity with its zebrafish counterpart, suggesting a conserved role between species. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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DULLARD Rabbit pAb(bs-11828R)-50ul/100ul/200ul
￥1180 - 2800
