TMEM59L Rabbit pAb(bs-11648R)-50ul/100ul/200ul

TMEM59L Rabbit pAb(bs-11648R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-11648R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-11648R
    英文名称TMEM59L Rabbit pAb
    中文名称跨膜蛋白59样蛋白抗体
    英文别名BSMAP; Brain-specific membrane-anchored protein; C19orf4; TM59L_HUMAN; Tmem59l; Transmembrane protein 59-like.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Pig, Cow, Horse, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human TMEM59L
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量35 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease > Amyloid

    Signal Transduction > Protein Trafficking > Golgi Proteins

    Tags & Cell Markers > Subcellular Markers > Organelles > Golgi

    亚细胞定位Golgi apparatus membrane.
    组织特异性Expressed preferentially at high level in the brain.
    翻译后修饰Belongs to the TMEM59 family.
    相似性Belongs to the TMEM59 family.
    功能Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BSMAP is a 342 amino acid type-I membrane glycoprotein that localizes to organelle membranes and belongs to the TMEM59 family. Expressed at high levels in brain tissue, BSMAP is thought to play a role in brain function and central nervous system activity. The gene encoding BSMAP maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    TMEM59L Rabbit pAb(bs-11648R)-
    Sample: Hela Cell(Human)Lysate at 30 ug
    Primary: Anti-TMEM59L (bs-11648R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 35kD
    Observed band size: 37kD

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