Sample:
Lane 1: Human U-2 OS cell lysates
Lane 2: Human HeLa cell lysates
Lane 3: Human HUVEC cell lysates
Lane 4: Human A431 cell lysates
Primary: Anti-FSTL1 (bs-6050R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34 kDa
Observed band size: 47 kDa
- ￥1180 - 2800
- Bioss
- bs-6050R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6050R |
| 英文名称 | FSTL1 Rabbit pAb |
| 中文名称 | 卵泡抑素相关蛋白1抗体 |
| 英文别名 | FSTL1; TSC-36; Follistatin like 1; Follistatin related protein; Follistatin-like protein 1; Follistatin-related protein 1; FRP; FSL1; FSTL1; FSTL1_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FSTL1/FRP |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 34 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Ischemia / Reperfusion Cardiovascular > Blood Cell Biology > Cell Cycle > Cell differentiation |
| 亚基 | Interacts with SCN10A. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Overexpressed in synovial tissues from rheumatoid arthritis. |
| 相似性 | Contains 2 EF-hand domains. Contains 1 follistatin-like domain. Contains 1 Kazal-like domain. Contains 1 VWFC domain. |
| 功能 | May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TSC-36 is a secreted extracellular glycoprotein. The amino acid sequence of TSC-36 is similar to follistatin, an inhibitor of activin, as it contains a follistatin module. TSC-36 is a heparin-binding protein suggested to have a role in the negative regulation of cellular growth, as its expression is induced in response to TGF-b1. In addition, TSC-36 is not found in small cell lung cancer (SCLC) cells, a highly aggressive neoplasm, but is detected in some non-small cell lung cancer (NSCLC) cells, a moderately aggressive neoplasm.. May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验相关实验
内源性FSTL1 通过激活钠‐钾泵引起膜超极化调节痛觉信息传递
的重组FSTL1 蛋白孵育培养的大鼠DRG 神经元，BS3 交联与细胞膜上受体结合的FSTL1，裂解细胞。细胞裂解物做Western blotting，用抗Myc 的抗体进行免疫共沉淀（IP），在140 kD 处发现阳性条带。于FSTL1 约40 kD，因此推断FSTL1 结合了约100 kD 的蛋白。相同的方法富集交联复合物，用质谱分析发现结合蛋白可能为NKA 的α1 亚基。放免实验和co‐IP 实验证明了与FSTL1 结合的蛋白正是NKA 的α1 亚基。 由于FSTL1 能通过清亮小泡
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
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FSTL1 Rabbit pAb(bs-6050R)-50ul/100ul/200ul
￥1180 - 2800
