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GPR27 Rabbit pAb(bs-13528R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-13528R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-13528R
    英文名称GPR27 Rabbit pAb
    中文名称G蛋白偶联受体27抗体
    英文别名G protein coupled receptor 27; GPR 27; GPR27; GPR27_HUMAN; Probable G protein coupled receptor GPR27; Probable G-protein coupled receptor 27; SREB 1; SREB1; Super conserved receptor expressed in brain 1; GPCR GPR27.
    产品应用Flow-Cyt=3μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Cow)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SREB1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量40 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane.
    组织特异性Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-like GPR.

     

    应用推荐稀释比例
    {Flow-Cyt}{3μg/Test}

     

    产品细节图片1
    Blank control: RSC96 cells(blue).
    Primary Antibody: Rabbit Anti- GPR27 antibody(bs-13528R), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA;
    Isotype Control Antibody: Rabbit IgG (orange) ,used under the same conditions.
    Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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    图标文献和实验
    该产品被引用文献

    [IF={{ 5.2 }}] {Jun Pan. et al. Prognostic significance and immune characteristics of GPR27 in gastric cancer. AGING-US. 2023 Sep 15; 15(17): 9144–9166} {IHC} {Human}

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    文献支持
    GPR27 Rabbit pAb(bs-13528R)-50ul/100ul/200ul
    ¥1180 - 2800