- ￥1180 - 2800
- Bioss
- bs-12126R
- 2026年10月14日
企业认证
相关产品推荐更多 >
Carboxypeptidase H Rabbit pAb, AP conjugated(bs-6478R-AP)-100ul
￥2980
CHMP2A Rabbit pAb, BF405 conjugated(bs-13913R-BF405)-100ul
￥2980
P63 Mouse mAb, PE-Cy7 conjugated(bsm-33422M-PE-Cy7)-100ul
￥2980EME1 Rabbit pAb, APC conjugated(bs-7861R-APC)-100ul
￥2980
C7orf65 Rabbit pAb, RBITC conjugated(bs-15280R-RBITC)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
香烟烟雾如何加速声带纤维化？CD44-透明质酸轴是关键通路Takara 秋促来袭，提取+反转录+定量套装仅 1200 元abinScience 体内级抗体 全年锁价 低至 ￥1200阿拉丁 22万+ 科研级产品现货速发，品质严控、科研无忧- 详细信息
- 技术资料
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12126R |
| 英文名称 | Tomosyn/STXBP5 Rabbit pAb |
| 中文名称 | 突触融合蛋白结合蛋白5抗体 |
| 英文别名 | FLJ30922; Lethal(2) giant larvae protein homolog 3; LGL3; LLGL3; MGC141942; MGC141968; Nbla04300; STXBP5; Syntaxin binding protein 5; Syntaxin-binding protein 5; Tomosyn 1; STXB5_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Tomosyn/STXBP5 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 127 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with STX1A and STX1B via its v-SNARE homology domain. Part of a complex that contains STX1, STXBP5, SNAP25 and SYT1. Part of a complex that contains STXBP5, STX4A and SNAP23. |
| 亚细胞定位 | Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse. Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles. |
| 相似性 | Belongs to the WD repeat L(2)GL family._x000D_
Contains 1 v-SNARE coiled-coil homology domain._x000D_ Contains 14 WD repeats. |
| 功能 | Tomosyn plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release by inhibiting the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane, via the displacement of munc18 from syntaxin-1. There are three splice variants of tomosyn designated m-tomosyn, b-tomosyn and s-tomosyn. Although b-tomosyn is ubiquitously expressed, s-tomosyn and m-tomosyn are expressed primarily in brain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. Tomosyn, also known as STXBP5 (syntaxin binding protein 5), LLGL3 or LGL3, is a 1,151 amino acid protein that localizes to the cytoplasm, as well as to the cell junction, secretory vesicles and to the peripheral membrane and contains one v-SNARE coiled-coil homology domain and 14 WD repeats. Interacting with Syntaxin 1 and Syntaxin 1B, Tomosyn functions as a regulator of neurotransmitter release and calcium-dependent exocytosis. Additionally, Tomosyn inhibits membrane fusion and may play a role in the assembly of SNARE complexes between transport vesicles and the plasma membrane. Multiple isoforms of Tomosyn exist due to alternative splicing events. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
STXBP5 | Tomosyn Rabbit pAb(bs-12126R)-50ul/100ul/200ul
￥1180 - 2800
