SISP1 Rabbit pAb(bs-9898R)-50ul/100ul/200ul

SISP1 Rabbit pAb(bs-9898R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-9898R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-9898R
    英文名称SISP1 Rabbit pAb
    中文名称应激诱导分泌蛋白1抗体
    英文别名C10orf54; VISTA_HUMAN; Platelet receptor Gi24; stress induced secreted protein 1; UNQ730/PRO1412; V-type immunoglobulin domain-containing suppressor of T-cell activation; Stress-induced secreted protein-1; Sisp-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; B7-H5; B7H5; DD1alpha; GI24; PD-1H; PP2135; VISTA.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SISP1/GI24
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量31 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Membrane.
    相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    SISP1 Rabbit pAb(bs-9898R)-50u
    25 ug total protein per lane of various lysates (see on figure) probed with SISP1 polyclonal antibody, unconjugated (bs-9898R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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