产品封面图
文献支持

Calponin 1 + 2 + 3 Rabbit pAb(

bs-4902R)-50ul/100ul/200ul
收藏
  • ￥1180 - 2800
  • Bioss已认证
  • bs-4902R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
10 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-4902R
    英文名称Calponin 1 + 2 + 3 Rabbit pAb
    中文名称钙结合蛋白Calponin抗体
    英文别名smooth muscle; Basic calponin; Calponin 1; Calponin 2; Calponin 3; Calponin1; Calponin2; Calponin3; Calponin-1; Calponin-2; Calponin-3; Calponin 1 basic smooth muscle; Calponin H1; Calponin H1 smooth muscle; Calponins basic; CNN 1; Cnn1; CNN2_HUMAN; Sm Calp; SMCC.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Dog, Pig, Cow, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Calponin 1/2/3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量34 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Heart > Contractility > Contractile Proteins > Actins

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins

    组织特异性Heart and smooth muscle.
    相似性Belongs to the calponin family.
    Contains 3 calponin-like repeats.
    Contains 1 CH (calponin-homology) domain.
    功能Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Positive control: H9C2(2% P‌‌araformaldehyde-fixed )
    Isotype Control Antibody: Rabbit IgG; Dilution: 1μg in 100 μl 1 X PBS containing 0.5% BSA
    Secondary Antibody: Goat anti-rabbit IgG-FITC; Dilution: 1:200 in 1 X PBS containing 0.5% BSA
    Primary Antibody: rabbit Anti-Calponin 1 + 2 + 3 (bs-4902R); Dilution: 1μg in 100 μl 1X PBS containing 0.5% BSA
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (Rat heart); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Calponin 1 + 2 + 3) Polyclonal Antibody, Unconjugated (bs-4902R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    [IF={{ 10.6 }}] {Wang Weitie. et al. 3D-printing hydrogel programmed released exosomes to restore aortic medial degeneration through inhibiting VSMC ferroptosis in aortic dissection. J NANOBIOTECHNOL. 2024 Dec;22(1):1-16} {WB} {Mouse}

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Calponin 1 rabbit pAb
    询价
    武汉佰瑞得生物技术有限公司
    2025年07月13日询价
    Calponin Rabbit pAb
    ￥600
    杭州戴格生物技术有限公司
    2025年12月17日询价
    Calponin 2 Rabbit pAb
    询价
    上海圻明生物科技有限公司
    2025年07月11日询价
    Calponin 1 rabbit pAb
    ￥1260
    杭州臻优品生物科技有限公司
    2025年06月24日询价
    Calponin 1 rabbit pAb
    询价
    ImmunoWay Biotechnology Company
    2025年07月12日询价
    文献支持
    Calponin 1 + 2 + 3 Rabbit pAb(bs-4902R)-50ul/100ul/200ul
    ￥1180 - 2800