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- bs-11088R
- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-11088R |
| 英文名称 | LRFN3 Rabbit pAb |
| 中文名称 | 神经突触粘附样分子4抗体 |
| 英文别名 | SALM4; Fibronectin type II immunoglobulin and leucine rich repeat domains 1; Fibronectin type II, immunoglobulin and leucine rich repeat domains 1; FIGLER1; Leucine rich repeat and fibronectin type III domain containing 3; Leucine-rich repeat and fibronectin type-III domain-containing protein 3; Lrfn3; LRFN3_HUMAN; Synaptic adhesion-like molecule 4. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human LRFN3/SALM4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 65 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Can form heteromeric complexes with LRFN1, LRFN2, LRFN4 and LRFN5. Able to form homomeric complexes across cell junctions, between adjacent cells. Does not interact with DLG4 (By similarity). |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein (By similarity). Cell projection, axon (By similarity). Cell projection, dendrite (By similarity). Cell junction, synapse (By similarity). Cell junction, synapse, presynaptic cell membrane (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Belongs to the LRFN family. Contains 1 fibronectin type-III domain. Contains 1 Ig-like (immunoglobulin-like) domain. Contains 7 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. |
| 功能 | Cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | LRFN3 is a 628 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing seven LRR (leucine-rich) repeats, LRFN3 also contains one fibronectin type-III domain, one Ig-like (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. As a cell adhesion molecule that mediates homophilic cell-cell adhesion in a Ca2+-independent manner, LRFN3 promotes neurite outgrowth in hippocampal neurons. LRFN3 forms homomeric complexes across cell junctions (between adjacent cells), and can form heteromeric complexes with LRFN1, LRFN2, LRFN4 and LRFN5. The gene that encodes LRFN3 consists of more than 8,000 bases and maps to human chromosome 19q13.12. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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