Blank control: 293FT(blue)
Isotype Control Antibody: Rabbit IgG(orange) ;
Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue),
Dilution: 1:100 in 1 X PBS containing 0.5% BSA ;
Primary Antibody Dilution: 5μl in 100 μL1X PBS containing 0.5% BSA(green).
- ￥1180 - 2800
- Bioss
- bs-1710R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 应用范围：
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1710R |
| 英文名称 | CCR10 Rabbit pAb |
| 中文名称 | 细胞表面趋化因子受体10抗体 |
| 英文别名 | C-C chemokine receptor 10; C C chemokine receptor type 10; C C CKR 10; CC chemokine receptor 10; CC CKR 10; CCR 10; CCR-10; CCR10; Chemokine(C C motif) receptor 10; G protein coupled receptor 2; G protein-coupled receptor 2; GPR 2; GPR2. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=5μg/Test Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Pig, Cow, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CCR-10 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 40 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {Flow-Cyt} | {5μg/Test} |
Paraformaldehyde-fixed, paraffin embedded (mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCR10) Polyclonal Antibody, Unconjugated (bs-1710R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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文献和实验相关实验
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
- a ) ELISA 48T/96T 1300/2300 进口分装 F1697 大鼠可溶性肿瘤坏死因子- 受体 (rat TNF-R ) ELISA 48T/96T 2000/3000 进口分装 F1698 大鼠组织纤溶酶原激活剂(rat t-PA) ELISA 48T/96T 2000/3000 进口分装 F1699 大鼠血小板生成素(rat TPO) ELISA 48T/96T 2000/3000 进口分装 F1710 大鼠尿激酶型纤溶酶原(rat
- a ) ELISA 48T/96T 1300/2300 进口分装 F1697 大鼠可溶性肿瘤坏死因子- 受体 (rat TNF-R ) ELISA 48T/96T 2000/3000 进口分装 F1698 大鼠组织纤溶酶原激活剂(rat t-PA) ELISA 48T/96T 2000/3000 进口分装 F1699 大鼠血小板生成素(rat TPO) ELISA 48T/96T 2000/3000 进口分装 F1710 大鼠尿激酶型纤溶酶原(rat
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CCR10 Rabbit pAb(bs-1710R)-50ul/100ul/200ul
￥1180 - 2800
