MMP24 Rabbit pAb(bs-10718R)-50ul/100ul/200ul

MMP24 Rabbit pAb(bs-10718R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-10718R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-10718R
    英文名称MMP24 Rabbit pAb
    中文名称基质金属蛋白酶-24抗体
    英文别名Matrix metallopeptidase 24(membrane inserted); Matrix metallopeptidase 24; Membrane type 5 matrix metalloproteinase; Membrane type matrix metalloproteinase 5; Membrane-type matrix metalloproteinase 5; Membrane-type-5 matrix metalloproteinase; MMP 24; MMP 25; MMP-24; Mmp24; MMP24_HUMAN; MMP25; MT MMP5; MT-MMP 5; MT5 MMP; MT5-MMP; MT5MMP; MTMMP5; Processed matrix metalloproteinase-24.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MMP24
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量57 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > ECM > Extracellular matrix > MMPs

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Metalloprotease > MMPs

    Neuroscience > Cell Adhesion Proteins > ECM Proteins

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP

    亚细胞定位Cell membrane; Single-pass type I membrane protein; Extracellular side.
    Processed matrix metalloproteinase-24: Secreted, extracellular space, extracellular matrix. Note=Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.
    组织特异性Expressed in brain. Expressed at low level in testis.
    翻译后修饰The precursor is cleaved by a furin endopeptidase.
    相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
    功能Activates progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    ¥1180 - 2800