Sample:
intestine (mouse) Lysate at 40 ug
placenta (mouse) Lysate at 40 ug
Primary: Anti-GALNT6 (bs-16222R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 71 kD
Observed band size: 71 kD
- ￥1180 - 2800
- Bioss
- bs-16222R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-16222R |
| 英文名称 | GALNT6 Rabbit pAb |
| 中文名称 | GalNAc-T6蛋白抗体 |
| 英文别名 | GALNAC T6; GalNAc transferase 6; GalNAc-T6; GalNAcT6; GALNT 6; GALNT6; GALT6_HUMAN; Polypeptide GalNAc transferase 6; Polypeptide N acetylgalactosaminyltransferase 6; Polypeptide N-acetylgalactosaminyltransferase 6; pp GaNTase 6; pp-GaNTase 6; Protein UDP acetylgalactosaminyltransferase 6; Protein-UDP acetylgalactosaminyltransferase 6; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 6; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 6(GalNAc T6); UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human GALNT6 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 71 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Tags & Cell Markers > Subcellular Markers > Organelles > Golgi |
| 亚细胞定位 | Golgi apparatus membrane. |
| 组织特异性 | Expressed in placenta and trachea. Weakly expressed in brain and pancreas. Expressed in fibroblast. Weakly or not expressed in lung, liver, muscle, kidney, spleen, thymus, prostate, testis, ovary, intestine, colon, leukocyte, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland and bone marrow. |
| 相似性 | Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. |
| 功能 | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 4.6 }}] {Ziyuan Tong. et al. GALNT6, transcriptionally inhibited by KLF9, promotes osteosarcoma progression by increasing EFEMP1 expression via O-glycosylation modification. BBA-MOL CELL RES. 2024 Nov;:119879} {IHC} {Mouse}
[IF={{ 4.5 }}] {Luhaoran Sun. et al. N-acetylgalactosaminyltransferase GALNT6 is a potential therapeutic target of clear cell renal cell carcinoma progression. CANCER SCI. 2024 Aug;:} {IHC} {Mouse}
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GALNT6 Rabbit pAb(bs-16222R)-50ul/100ul/200ul
￥1180 - 2800
