TOLLIP Rabbit pAb(bs-18168R)-50ul/100ul/200ul产品图

TOLLIP Rabbit pAb(bs-18168R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-18168R
  • 2026年10月14日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-18168R
    英文名称Tollip Rabbit pAb
    中文名称Toll蛋白相互作用蛋白抗体
    英文别名Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP_HUMAN; Toll interacting protein; Toll-interacting protein; tollip.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Xenopus laevis)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Tollip
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量30 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Immunoglobulins > Receptors

    Immunology > Innate Immunity > Cytokines > Interleukins

    Immunology > Innate Immunity > TLR Signaling

    亚细胞定位Cytoplasm.
    翻译后修饰Phosphorylated by IRAK1 upon stimulation by IL-1 or microbial products.
    相似性Belongs to the tollip family.
    _x000D_ Contains 1 C2 domain.
    _x000D_ Contains 1 CUE domain.
    功能Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [provided by RefSeq, Aug 2011]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Tollip) Polyclonal Antibody, Unconjugated (bs-18168R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    ¥1180 - 2800