KATNA1 Rabbit pAb(bs-9308R)-50ul/100ul/200ul

KATNA1 Rabbit pAb(bs-9308R)-50

ul/100ul/200ul
收藏
  • ￥1180 - 2800
  • Bioss已认证
  • bs-9308R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
avatar
北京博奥森生物技术有限公司
品牌商
9 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 技术资料
    • 应用范围：

      产品信息以Bioss网站为准

    • 规格：

      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-9308R
    英文名称KATNA1 Rabbit pAb
    中文名称剑蛋白p60亚基A1抗体
    英文别名Katanin p60 A1; Katanin p60 ATPase containing subunit A1; Katanin p60 ATPase-containing subunit A1; Katanin p60 subunit A1; KATNA1; KTNA1_HUMAN; p60 katanin.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KATNA1/Katanin p60 A1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量56 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex).
    亚细胞定位Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1.
    翻译后修饰Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted to proteasomal degradation.
    相似性Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
    功能Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth (By similarity).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin p60 A1, also known as KATNA1, is a 491 amino acid protein that belongs to the AAA ATPase family and is involved in microtubule regulation. Localized to the cytoplasm and to the centrosome, Katanin p60 A1 functions to sever and disassemble microtubules in an ATP-dependent manner, thus promoting the rapid reorganization of cellular microtubule arrays and playing an important role in microtubule release from the centrosome after nucleation. Katanin p60 A1, which exists as two alternatively spliced isoforms, can homooligomerize into hexameric rings whose activity is stimulated by the presence of microtubules.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:50-200}

     

    KATNA1 Rabbit pAb(bs-9308R)-50
    P‌‌araformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KATNA1) Polyclonal Antibody, Unconjugated (bs-9308R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    KATNA1 Rabbit pAb(bs-9308R)-50
    P‌‌araformaldehyde-fixed, paraffin embedded (Human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KATNA1) Polyclonal Antibody, Unconjugated (bs-9308R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    KATNA1 Rabbit pAb(bs-9308R)-50
    Sample:
    Fetal brain (Mouse) Lysate at 40 ug
    Primary: Anti-KATNA1 (bs-9308R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size:56 kD
    Observed band size: 56 kD
    KATNA1 Rabbit pAb(bs-9308R)-50
    Sample:
    Lane 1: Mouse Cerebrum tissue lysates
    Lane 2: Mouse Liver tissue lysates
    Lane 3: Rat Cerebrum tissue lysates
    Lane 4: Rat Liver tissue lysates
    Lane 5: Human HeLa cell lysates
    Lane 6: Human MCF-7 cell lysates
    Lane 7: Human Jurkat cell lysates
    Primary: Anti-KATNA1 (bs-9308R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 56 kDa
    Observed band size: 50 kDa
    KATNA1 Rabbit pAb(bs-9308R)-50
    P‌‌araformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (KATNA1) Polyclonal Antibody, Unconjugated (bs-9308R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    KATNA1 Rabbit pAb
    ￥600
    杭州戴格生物技术有限公司
    2025年04月09日询价
    KATNA1 Rabbit pAb
    询价
    上海圻明生物科技有限公司
    2025年07月14日询价
    KATNA1 rabbit pAb
    询价
    ImmunoWay Biotechnology Company
    2025年07月12日询价
    KATNA1 Rabbit Monoclonal Antibody
    ￥1999
    无锡傲锐东源生物科技有限公司
    2025年07月11日询价
    KATNA1 Rabbit Polyclonal Antibody
    ￥500
    北京百奥创新科技有限公司
    2025年05月21日询价
    KATNA1 Rabbit pAb(bs-9308R)-50ul/100ul/200ul
    ￥1180 - 2800