Sample:
_x000D_
NIH/3T3(Mouse) Cell Lysate at 30 ug
_x000D_
Primary: Anti-CDMP1 (bs-6580R) at 1/300 dilution
_x000D_
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_
Predicted band size: 55 kD
_x000D_
Observed band size: 60 kD
- ￥1180 - 2800
- Bioss
- bs-6580R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6580R |
| 英文名称 | CDMP1 Rabbit pAb |
| 中文名称 | 软骨衍生形态发生蛋白1/GDF 5抗体 |
| 英文别名 | Cartilage derived morphogenetic protein 1; Cartilage-derived morphogenetic protein 1; CDMP-1; CDMP1; GDF-5; Gdf 5; GDF5_HUMAN; Growth differentiation factor 5; Growth/differentiation factor 5; LAP4; Radotermin. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CDMP1/GDF5 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 55 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Homodimer; disulfide-linked (By similarity). |
| 亚细胞定位 | Secreted._x000D_ |
| 组织特异性 | Predominantly expressed in long bones during embryonic development._x000D_ |
| 相似性 | Belongs to the TGF-beta family. |
| 功能 | Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet.Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
_x000D_ NIH/3T3(Mouse) Cell Lysate at 30 ug
_x000D_ LOVO(Human) Cell Lysate at 30 ug
_x000D_ Primary: Anti-CDMP1 (bs-6580R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 55 kD
_x000D_ Observed band size: 60 kD
_x000D_ NIH/3T3(Mouse) Cell Lysate at 30 ug
_x000D_ LOVO(Human) Cell Lysate at 30 ug
_x000D_ Primary: Anti-CDMP1 (bs-6580R) at 1/1000 dilution
_x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
_x000D_ Predicted band size: 55 kD
_x000D_ Observed band size: 60 kD
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GDF5 | BMP-14 Rabbit pAb(bs-6580R)-50ul/100ul/200ul
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