Blank control: Lovo Cells(blue).
Primary Antibody: Rabbit Anti-Glypican 6/AF647 Conjugated antibody (bs-7686R-AF647), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG/AF647(orange) ,used under the same conditions.
- ￥1180 - 2800
- Bioss
- bs-2177R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2177R |
| 英文名称 | Glypican 6 Rabbit pAb |
| 中文名称 | 磷脂酰基醇蛋白聚糖-6抗体 |
| 英文别名 | GPC 6; Glypican6; Glypican-6; Glypican 6 [Precursor]; Glypican proteoglycan 6; GPC 6; GPC6; MGC126288; Secreted glypican 6. |
| 产品应用 | Flow-Cyt=1μg/Test Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Glypican 6 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 56 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > HSPGs Signal Transduction > Growth Factors/Hormones > FGF |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted glypican-6: Secreted, extracellular space. |
| 组织特异性 | Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood leukocytes. |
| 相似性 | Belongs to the glypican family. |
| 功能 | Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti proteases. The glypicans comprise a family of glycosylphosphatidylinositol anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1μg/Test} |
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文献和实验该产品被引用文献
[IF={{ preprint }}] {Brandon B. Holmes. et al.β-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity.biorxiv.2025 Feb 25:2025.02.20.637701.} {ICC} {Human}
[IF={{ 6.27 }}] {Erik M. Lehmkuhl. et al. TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6. Acta Neuropathol Com. 2021 Dec;9(1):1-21} {IHC} {Human}
[IF={{ 45.5 }}] {Jessica E. Rexach. et al. Cross-disorder and disease-specific pathways in dementia revealed by single-cell genomics. CELL. 2024 Oct;187:5753-5774.e28} {IF} {Human}
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Glypican 6 Rabbit pAb(bs-2177R)-50ul/100ul/200ul
￥1180 - 2800
