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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-1326R |
| 英文名称 | FGF10 Rabbit pAb |
| 中文名称 | 成纤维细胞生长因子10抗体 |
| 英文别名 | Fibroblast growth factor 10; FGF 10; FGF-10; Keratinocyte growth factor 2; KGF 2; BB213776; fd11d03; FGF10_HUMAN; wu:fd11d03; zgc:109774. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, GuineaPig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human FGF10 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 23 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Growth factors > FGF Cardiovascular > Angiogenesis > Growth Factors > FGF > FGF Signal Transduction > Growth Factors/Hormones > FGF Stem Cells > Embryonic Stem Cells > Secreted |
| 亚基 | Interacts with FGFR1 and FGFR2. Interacts with FGFBP1. |
| 亚细胞定位 | Secreted (Potential). |
| 相似性 | Belongs to the heparin-binding growth factors family. |
| 功能 | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Primary: Anti-FGF10(bs-1326R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 17 kD

Primary: Anti-FGF10(bs-1326R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 18 kD
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文献和实验[IF={{ 2.91 }}] {Zhang Y et al. Comparative study on seasonal hair follicle cycling by analysis of the transcriptomes from cashmere and milk goats. Genomics. 2019 Feb 16. pii: S0888-7543(18)30576-7.} {WB} {Goat}
[IF={{ 2.173 }}] {Liu K et al. FGF10 regulates thalamocortical axon guidance in the developing thalamus. Neurosci Lett. 2020 Jan 18;716:134685.} {IF} {chick}
[IF={{ 1.7 }}] {Huang, Jian, et al. "Expression of bioactive recombinant human fibroblast growth factor 10 in Carthamus tinctorius L. seeds." Protein Expression and Purification (2015).} {WB} {=""}
[IF={{ 1.559 }}] {Chen et al. Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis. (2016) Mol.Med.Re. 14:2929-36} {IF} {Mouse}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
Characterization and Validation of Cre‐Driver Mouse Lines
‐injected Ins1‐CreERT2 /ROSA26 mice revealed specific Cre protein content and Cre activity restricted to the islets of Langerhans. ISH procedures have been described elsewhere (Chotteau‐Lelievre et al., ; Gofflot et al., ). For IHC, primary rabbit anti‐Cre
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
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