Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human Raji cell lysates
Primary: Anti-CXCR1 (bs-1009R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 61 kDa
- ￥1180 - 2800
- Bioss
- bs-1009R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1009R |
| 英文名称 | CXCR1 Rabbit pAb |
| 中文名称 | 细胞表面趋化因子受体1抗体 |
| 英文别名 | C C; C C CKR 1; CCCKR1; CD 181; CD128; CD181; CDw128a; Chemokine(C X C motif) receptor 1; Chemokine(C X C) receptor 1; Chemokine receptor 1; CKR 1; CMKAR1; CXCR 1; High affinity interleukin 8 receptor A; IL 8 receptor type 1; IL 8R A; IL-8RA; IL8 receptor; IL8 receptor type 1; IL8R1; IL8RA; IL8RBA; Interleukin 8 receptor alpha; Interleukin 8 receptor type 1. Interleukin 8 receptor type A; CXCR1_HUMAN; C-C; CD181; CKR-1; IL8R1; CDw128a; C-C-CKR-1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CXCR1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 40 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor immunology > Cytokines Immunology > Innate Immunity > Chemokines > Alpha Chemokines (CXC) |
| 亚细胞定位 | Cell membrane. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 8.786 }}] {Guangxu Xiao. et al. CXCR1 and its downstream NF-κB inflammation signaling pathway as a key target of Guanxinning injection for myocardial ischemia/reperfusion injury.. FRONT IMMUNOL. 2022 Oct;13:1007341-1007341} {WB,IHC,IF} {Mouse}
[IF={{ 3.37 }}] {Chengfei Xu. et al. CXCR1 participates in bone cancer pain induced by Walker 256 breast cancer cells in female rats. MOL PAIN. ;():} {WB,IF} {Rat}
[IF={{ 2.57 }}] {Schneberger, D., et al. "CXCR1/CXCR2 antagonist CXCL8 (3-74) K11R/G31P blocks lung inflammation in swine barn dust-instilled mice." Pulmonary Pharmacology & Therapeutics (2015).} {IHC} {="Mouse"}
[IF={{ 2.24 }}] {Tang, Cui, et al. "High expression of GPER1, EGFR and CXCR1 is associated with lymph node metastasis in papillary thyroid carcinoma." International Journal of Clinical and Experimental Pathology 7.6 (2014): 3213-3223.} {IHC} {="Human"}
[IF={{ 2.24 }}] {Tang et al. High expression of GPER1, EGFR and CXCR1 is associated with lymph node metastasis in papillary thyroid carcinoma. (2014) Int.J.Clin.Exp.Patho. 7:3213-23} {IHC} {Human}
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CXCR1 Rabbit pAb(bs-1009R)-50ul/100ul/200ul
￥1180 - 2800
