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LDHA Rabbit pAb(bs-1810R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1810R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1810R
    英文名称LDHA Rabbit pAb
    中文名称乳酸脱氢酶抗体
    英文别名Lactate Dehydrogenase; Lactate Dehydrogenase Isoenzyme V; Lactate Dehydrogenase isozyme H4; L lactate dehydrogenase A chain; Lactate dehydrogenase A; Lactate dehydrogenase A chain; LDH A; LDH heart subunit; LDH M; LDHM; LDH muscle subunit; LDH1; LDHA; PIG 19; PIG19; Proliferation inducing gene 19 protein; TRG 5; TRG5; LDHA_HUMAN.
    产品应用IHC-P=1:400-800, IHC-F=1:400-800, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Pig, Cow, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LDHA
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量37 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates

    Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Dehydrogenase Kits

    Kits/ Lysates/ Other > Kits > Cell Metabolism Kits > Oxidative Stress Assay Kits > NADP/NADPH

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Energy Metabolism

    亚基Homotetramer.
    亚细胞定位Cytoplasm.
    翻译后修饰ISGylated.
    相似性Belongs to the LDH/MDH superfamily. LDH family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq].

     

    应用推荐稀释比例
    {IHC-P}{1:400-800}
    {IHC-F}{1:400-800}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

    产品细节图片1
    P‌‌araformaldehyde-fixed, paraffin embedded (mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LDHA) Polyclonal Antibody, Unconjugated (bs-1810R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (rat pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LDHA) Polyclonal Antibody, Unconjugated (bs-1810R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    该产品被引用文献

    [IF={{ 5.6 }}] {Xuemei Yang. et al. Baicalin promotes anti-tumor immunity in hepatocellular carcinoma through HIF-1α/Lactate/CXCL9 axis. BIOCHEM PHARMACOL. 2025 Jul;:117157} {WB} {Human}

    [IF={{ 5.2 }}] {Mengqi Li. et al. Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels. CELLS-BASEL. 2025 Jan;14(11):832} {IF,WB,IHC} {Bovine}

    [IF={{ 2.5 }}] {Nannan Li. et al. Revealing the effects of lactate on bovine SCNT embryo development through transcriptome sequencing analyses. THERIOGENOLOGY. 2025 Apr;236:137} {IF} {Bovine}

    [IF={{ 2.136 }}] { Yu CL et al. AMP-activated protein kinase negatively regulates heat treatment-induced lactate secretion in cultured boar sertoli cells. Theriogenology. 2018 Nov;121:35-41.} {WB} {boar}

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    文献支持
    LDHA Rabbit pAb(bs-1810R)-50ul/100ul/200ul
    ¥1180 - 2800