AQP2 Rabbit pAb(bs-0261R)-50ul/100ul/200ul产品图
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AQP2 Rabbit pAb(bs-0261R)-50ul

/100ul/200ul
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  • ￥1180 - 2800
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  • bs-0261R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-0261R
    英文名称AQP2 Rabbit pAb
    中文名称水通道蛋白-2抗体
    英文别名ADH water channel; AQP 2; AQP-2; AQP CD; AQPCD; Aquaporin 2 collecting duct; Aquaporin CD; Aquaporin2; Aquaporine 2; Collecting duct water channel protein; MGC34501; Water channel protein for renal collecting duct; WCH CD; WCHCD.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human AQP2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量30 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane.
    组织特异性Expressed in renal collecting tubules.
    翻译后修饰Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent.
    相似性Belongs to the MIP/aquaporin (TC 1.A.8) family.
    功能Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus. Belongs to the MIP/aquaporin (TC 1.A.8) family.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: rat kidney tissue; 4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-AQP-2 Polyclonal Antibody, Unconjugated(bs-0261R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    _x000D_ _x000D_
    产品细节图片2
    Sample:
    _x000D_ Kidney (Mouse) Lysate at 40 ug
    _x000D_ 293T(Human) Cell Lysate at 30 ug
    _x000D_ Primary: Anti- Aquaporin 2 (bs-0261R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 30 kD
    _x000D_ Observed band size: 32 kD
    _x000D_
    产品细节图片3
    Sample: Heart (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti-Aquaporin 2 (bs-0261R) at 1/300 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 30 kD
    _x000D_ Observed band size: 35 kD
    _x000D_

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    [IF=2.386] Kai Zhang. et al. Investigation of Neuroprotective Effects of Erythropoietin on Chronic Neuropathic Pain in a Chronic Constriction Injury Rat Model. J Pain Res. 2020; 13: 3147–3155 WB Rat

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    AQP2 Rabbit pAb(bs-0261R)-50ul/100ul/200ul
    ￥1180 - 2800