MRGPRG | GPR169/MRGG Rabbit pAb(bs-20883R)-50ul/100ul/200ul产品图

MRGPRG | GPR169/MRGG Rabbit pA

b(bs-20883R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-20883R
  • 2026年10月13日
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    • 技术资料
    • 规格:

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-20883R
    英文名称MRGPRG Rabbit pAb
    中文名称G蛋白偶联受体169抗体
    英文别名G protein coupled receptor 169; G protein coupled receptor MRGG; G-protein coupled receptor 169; GPR169; Mas related G protein coupled receptor member G; MAS related GPR member G; Mas-related G-protein coupled receptor member G; MRGG; MRGPRG.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 (Human)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human MRGPRG
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量32 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Cell membrane.
    相似性Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
    功能Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料MRGG is a 289 amino acid multi-pass membrane protein that functions as an orphan receptor. A member of the G-protein coupled receptor 1 family and Mas subfamily, MRGG is implicated in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGG maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {ICC/IF}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    MRGPRG | GPR169/MRGG Rabbit pAb(bs-20883R)-50ul/100ul/200ul
    ¥1180 - 2800