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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-18831R |
| 英文名称 | RPS6KC1 Rabbit pAb |
| 中文名称 | p52核糖体蛋白S6激酶抗体 |
| 英文别名 | p52 S6 kinase; 52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1_HUMAN; Ribosomal protein S6 kinase 52kD polypeptide 1; Ribosomal protein S6 kinase 52kDa polypeptide 1; Ribosomal protein S6 kinase delta 1; Ribosomal protein S6 kinase delta-1; Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK 118; RPK118; RPS6KC1; S6K-delta-1; SPHK1 binding protein; SPHK1-binding protein. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human RPS6KC1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 119 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures. |
| 组织特异性 | Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. |
| 相似性 | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. Contains 1 MIT domain. Contains 2 protein kinase domains. Contains 1 PX (phox homology) domain. |
| 功能 | May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | p52 S6 kinase, also known as RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) or RPK118, is a 1,066 amino acid member of the Ser/Thr kinase family that localizes to both the cytoplasm and the nucleus and contains one MIT domain, one PX domain and two protein kinase domains. Expressed at high levels in brain, placenta, heart, testis, kidney, liver and skeletal muscle, p52 S6 kinase catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |

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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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