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- bs-18776R
- 2025年10月24日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-18776R |
| 英文名称 | MEGF6/EGFL3 Rabbit pAb |
| 中文名称 | EGF蛋白样3抗体 |
| 英文别名 | EGF-like protein 3; EGFL3; Epidermal growth factor-like protein 3; Megf6; MEGF6_HUMAN; Multiple EGF-like domains protein 6; Multiple epidermal growth factor-like domains protein 6. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Cow, Horse, Sheep, GuineaPig) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MEGF6/EGFL3 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 158 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Secreted |
| 相似性 | Contains 27 EGF-like domains. Contains 1 EMI domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | EGFL3 (epidermal growth factor-like protein 3), also known as MEGF6 (multiple epidermal growth factor-like domains protein 6), is a 1,541 amino acid secreted protein containing twenty-seven EGF-like domains and an EMI domain. Existing as two alternatively spliced isoforms, the gene encoding EGFL3 maps to human chromosome 1p36.32. The largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome, chromosome 1 contains about 3,000 genes. The rare aging disease Hutchinson-Gilford progeria, as well as Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome, are associated with chromosome 1. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 2.9 }}] {Wen Liang. et al. Disulfidptosis-based molecular clustering and prognostic signatures predict patient survival and the immune landscape in patients with colon cancer. Discover Oncology. 2025 Dec;16(1):1-20} {IHC} {Human}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
. Retrieved 2010-11-29. ^ Nielsen BS, Jørgensen S, Fog JU, Søkilde R, Christensen IJ, Hansen U, Brünner N, Baker A, Møller S, Nielsen HJ (October 2010). "High levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival
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