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- 2025年10月24日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-17743R |
| 英文名称 | MPV17L Rabbit pAb |
| 中文名称 | MPV17L蛋白抗体 |
| 英文别名 | FLJ39599; M LP homolog; M LPH; MGC70356; MLPH1; MLPH2; MPV 17L; Mpv17 like protein type 1; Mpv17 like protein type 2; MPV17 mitochondrial membrane protein like; MPV17L1. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MPV17L |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 22 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Isoform 1: Peroxisome membrane; Multi-pass membrane protein. |
| 组织特异性 | Isoform 1 is detected in the kidney (at protein level). Isoform 1 and isoform 2 are expressed in the kidney, heart, liver, lung, pancreas and skeletal muscle. |
| 相似性 | Belongs to the peroxisomal membrane protein PXMP2/4 family. |
| 功能 | MPV17L Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MPV17L is a 196 amino acid multi-pass membrane protein belonging to the peroxisomal membrane protein PXMP2/4 family. M-LPS (also known as M-LPH1) and M-LPL (also known as M-LPH2) are alternatively spliced isoforms of MPV17L and are ubiquitously expressed in human tissues, however only M-LPS exists at the protein level and mainly resides in kidney. MPV17L may be involved in protecting against mitochondrial oxidative stress and apoptosis, and participates in reactive oxygen species (ROS) metabolism by up- or down-regulating genes of antioxidant enzymes. MPV17L may play a role in the development of early-onset glomerulosclerosis, which is the hardening or formation of scar tissue of the glomerulus in the kidney. The gene encoding MPV17L maps to human chromosome 16p13.11. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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