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SLC38A1 Rabbit pAb(bs-19825R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-19825R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-19825R
    英文名称SLC38A1 Rabbit pAb
    中文名称溶质载体家族蛋白38成员1抗体
    英文别名Amino acid transporter A1; Amino acid transporter system A1; ATA 1; ATA1; N-system amino acid transporter 2; NAT 2; NAT2; S38A1_HUMAN; SAT 1; SAT1; SLC38A1; SNAT 1; SNAT1; Sodium-coupled neutral amino acid transporter 1; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse, Rat (Human, Pig, Cow, GuineaPig, Cat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SLC38A1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量54 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism

    Signal Transduction > Metabolism > Amino Acids

    Signal Transduction > Metabolism > Plasma Membrane > Channels

    亚细胞定位Cell membrane. Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain.
    组织特异性Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
    相似性Belongs to the amino acid/polyamine transporter 2 family.
    功能Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Liver (Mouse) Lysate at 40 ug
    Kidney (Mouse) Lysate at 40 ug
    Primary: Anti- SLC38A1 (bs-19825R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54kD
    Observed band size: 54kD
    产品细节图片2
    Sample:
    Lane 1: Mouse Cerebrum tissue lysates
    Lane 2: Mouse Cerebellum tissue lysates
    Lane 3: Rat Cerebrum tissue lysates
    Lane 4: Rat Cerebellum tissue lysates
    Primary: Anti-SLC38A1 (bs-19825R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54 kDa
    Observed band size: 50 kDa

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    该产品被引用文献

    [IF={{ 4.9 }}] {Paige L. Snider. et al. A Barth Syndrome Patient-Derived D75H Point Mutation in TAFAZZIN Drives Progressive Cardiomyopathy in Mice. INT J MOL SCI. 2024 Jan;25(15):8201} {WB} {Mouse}

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    文献支持
    SLC38A1 Rabbit pAb(bs-19825R)-50ul/100ul/200ul
    ¥1180 - 2800