LRIG2 Rabbit pAb(bs-1845R)-50ul/100ul/200ul

LRIG2 Rabbit pAb(bs-1845R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1845R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1845R
    英文名称LRIG2 Rabbit pAb
    中文名称LRIG2抗体
    英文别名DKFZp451C181; KIAA0806; LIG2; leucine-rich repeats and immunoglobulin-like domains protein 2 precursor; LRIG2_HUMAN; UFS2; LIG-2.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Dog, Pig, Cow, Horse, Rabbit, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human LRIG2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量117 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor biomarkers

    亚细胞定位Cell membrane; Single-pass type I membrane protein. Cytoplasm.
    组织特异性Detected in all tissues analyzed.
    相似性Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料LRIG2 is produced in all human glioma cell lines and localizes to perinuclear compartments, cytoplasmic compartments and the cell surface. It acts as a negative feedback regulator of signaling through enhanced receptor ubiquitination and accelerated intracellular degradation. LRIG2 may function as a tumour suppressor since it downregulates the expression of EGF and the related proteins ErbB-2, ErbB-3 and ErbB-4, which all inhibit cancer cells from growth, migration and invasion.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    LRIG2 Rabbit pAb(bs-1845R)-50u
    Sample:
    Lymph node (Mouse) Lysate at 40 ug
    Primary: Anti- LRIG2 (bs-1845R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 117 kD
    Observed band size: 117 kD
    LRIG2 Rabbit pAb(bs-1845R)-50u
    Sample:
    Thymus (Mouse) Lysate at 40 ug
    Primary: Anti- LRIG2 (bs-1845R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 117 kD
    Observed band size: 117 kD
    LRIG2 Rabbit pAb(bs-1845R)-50u
    Sample:
    Lane 1: Human HeLa cell lysates
    Lane 2: Human HepG2 cell lysates
    Primary: Anti-LRIG2 (bs-1845R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 117 kDa
    Observed band size: 117 kDa

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