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Lumican Rabbit pAb(bs-5890R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-5890R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号 bs-5890R
    英文名称 Lumican Rabbit pAb
    中文名称 基膜聚糖蛋白抗体
    英文别名 Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; LUM_HUMAN; Lumican; Lumican precursor; lumican proteoglycan; SLRR2D.
    产品应用 IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应 Rat (Human, Mouse, Pig, Cow, Horse, Rabbit)
    抗体来源 Rabbit
    免疫原 KLH conjugated synthetic peptide derived from human Lumican
    亚型 IgG
    性状 Liquid
    纯化方法 affinity purified by Protein A
    克隆类型 Polyclonal
    理论分子量 35 kDa
    浓度 1mg/ml
    储存液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Invasion/microenvironment > ECM > Extracellular matrix

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Other ECM Proteins

    亚细胞定位 Secreted. extracellular space. extracellular matrix.
    组织特异性 Cornea and other tissues.
    相似性 Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
    Contains 11 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
    保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.

     

    应用 推荐稀释比例
    {IHC-P} {1:100-500}
    {IHC-F} {1:100-500}
    {IF} {1:100-500}

     

    P‌‌araformaldehyde-fixed, paraffin embedded (rat retina tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Lumican) Polyclonal Antibody, Unconjugated (bs-5890R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    图标文献和实验
    该产品被引用文献

    [IF={{ 9.6 }}] {Leying Wang. et al. 3D Printed Biomimetic Bilayer Limbal Implants for regeneration of the Corneal Structure in Limbal Stem Cell Deficiency. ACTA BIOMATER. 2025 Jan;:} {IF} {Human}

    [IF={{ 5.2 }}] {Friederike Dehli. et al. Biobased photocrosslinkable gelatin-methacrylate hydrogels promote the growth and phenotype maintenance of human corneal keratocytes. Materials Advances. 2025 Apr;:} {IHC} {Human}

    [IF={{ 4.925 }}] {Ruixing Liu. et al. Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty. INVEST OPHTH VIS SCI. 2023 Mar;64(3):9-9} {FCM} {Rabbit}

    [IF={{ 4.9 }}] {María Dolores Salinas. et al. Expression of Lumican and Osteopontin in Perivascular Areas of the Glioblastoma Peritumoral Niche and Its Value for Prognosis. INT J MOL SCI. 2024 Dec;26(1):192} {IHC,IF} {Human,Mouse}

    [IF={{ 14.7 }}] {Riau Andri K.. et al. Impact of keratocyte differentiation on corneal opacity resolution and visual function recovery in male rats. NAT COMMUN. 2024 Jun;15(1):1-17} {ICC,IF} {Rat}

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    Lumican Rabbit pAb(bs-5890R)-50ul/100ul/200ul
    ¥1180 - 2800