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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-5890R |
| 英文名称 | Lumican Rabbit pAb |
| 中文名称 | 基膜聚糖蛋白抗体 |
| 英文别名 | Keratan sulfate proteoglycan lumican; KSPG lumican; LDC; LUM; LUM_HUMAN; Lumican; Lumican precursor; lumican proteoglycan; SLRR2D. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Rat (Human, Mouse, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Lumican |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 35 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 |
Cancer > Invasion/microenvironment > ECM > Extracellular matrix Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Other ECM Proteins |
| 亚细胞定位 | Secreted. extracellular space. extracellular matrix. |
| 组织特异性 | Cornea and other tissues. |
| 相似性 | Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. Contains 11 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 9.6 }}] {Leying Wang. et al. 3D Printed Biomimetic Bilayer Limbal Implants for regeneration of the Corneal Structure in Limbal Stem Cell Deficiency. ACTA BIOMATER. 2025 Jan;:} {IF} {Human}
[IF={{ 5.2 }}] {Friederike Dehli. et al. Biobased photocrosslinkable gelatin-methacrylate hydrogels promote the growth and phenotype maintenance of human corneal keratocytes. Materials Advances. 2025 Apr;:} {IHC} {Human}
[IF={{ 4.925 }}] {Ruixing Liu. et al. Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty. INVEST OPHTH VIS SCI. 2023 Mar;64(3):9-9} {FCM} {Rabbit}
[IF={{ 4.9 }}] {María Dolores Salinas. et al. Expression of Lumican and Osteopontin in Perivascular Areas of the Glioblastoma Peritumoral Niche and Its Value for Prognosis. INT J MOL SCI. 2024 Dec;26(1):192} {IHC,IF} {Human,Mouse}
[IF={{ 14.7 }}] {Riau Andri K.. et al. Impact of keratocyte differentiation on corneal opacity resolution and visual function recovery in male rats. NAT COMMUN. 2024 Jun;15(1):1-17} {ICC,IF} {Rat}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
secondary antibody review -- data from 99 publications
data
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