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- bs-14080R
- 2025年10月16日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-14080R |
| 英文名称 | CRYZ Rabbit pAb |
| 中文名称 | 晶状体蛋白ζ抗体 |
| 英文别名 | Crystallin zeta(quinone reductase); Crystallin zeta; Cryz; DKFZp779E0834; FLJ41475; NADPH:quinone reductase; QOR_HUMAN; Quinone oxidoreductase; Zeta crystallin; Zeta-crystallin; |
| 中文别名 | ζ-crystallin. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CRYZ |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 35 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism Neuroscience > Sensory System > Visual system Signal Transduction > Metabolism > Drug metabolism |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Only very low amounts in the lens. |
| 相似性 | Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. |
| 功能 | Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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